Reversing Age-Related
Vision Loss at its Source

Lento Bio develops small molecule therapeutics that repair molecular damage in the aging eye — beginning with the lens, where vision loss starts.

The lens stiffens and degrades universally with age. For most, this is the first major, symptomatic aging disorder they experience.

Our therapies target the root biology of this process, restoring natural physiology rather than masking symptoms.

Eyedrops that reverse age-induced vision loss — not mask it.

The Problem

Throw away your reading glasses

1.8 billion people worldwide have presbyopia — the universal, age-related loss of near vision. Everyone over 45 knows the feeling: arms stretched out, squinting at a menu, reaching for readers. It’s the one condition that spares no one. Today’s only option — corrective lenses — doesn’t treat the underlying cause, and limits everyday activities from reading your phone to working on a computer.

Because LB-01 fixes the lens itself
Your lens gets stiff with age — LB-01 reverses the molecular crosslinks that cause that stiffness
A flexible lens can focus again — restoring the near vision you had before presbyopia
Just an eye drop — no surgery, no special lenses, no daily workaround
Woman reading comfortably after discarding reading glasses

A small molecule that restores what aging takes away

LB-01 is a topical eye drop designed to reverse the molecular damage that stiffens the crystalline lens. Not a symptom mask — a repair mechanism inspired by the body’s own protective chemistry.

LB-01 eye drop bottle
Development Status
Our Pipeline
LB-01Presbyopia — topical eye drop
Discovery
IND-Enabling
Phase 1
Phase 2
Phase 3
LB-01Cataract prevention — topical eye drop
Discovery
IND-Enabling
Phase 1
Phase 2
Phase 3
LB-01 Nano-MPresbyopia — sustained-release wafer
Discovery
IND-Enabling
Phase 1
Phase 2
Phase 3
LB-01Presbyopia — small molecule
Discovery
IND-Enabling
Phase 1
Phase 2
Phase 3